The traffic signals controlling access to the St Marks retail park and University of Lincoln car park are reaching the end of their life and need to be replaced.
Work is set to start on Monday, February 4 and is expected to take four weeks to complete.
Although Rope Walk will remain open to traffic throughout the project, temporary lane closures will be in place, to ensure the safety of the workforce.
In addition, traffic will be stopped from turning right out of The Sidings (the access road to St Marks retail park) with those wishing to travel towards the High Street being diverted via the nearby roundabout and back on to Rope Walk.
Similarly, vehicles leaving the university car park will be prevented from turning right and will be diverted towards the High Street.
Traffic heading south will be directed to continue along the High Street, whereas those going north will be diverted along the East-West Link Road to Pelham Bridge.
A highways spokesperson said: “The lights are reaching the end of their life so we need to replace them.
“The new signals will be easier to maintain and much more energy efficient, saving on annual running costs.
“There will be some disruption while the work is carried out, and we apologise for any inconvenience caused in advance.
“We’d advise motorists to leave additional time for their journeys and use alternative routes where possible.”